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Bibcode:2003ACIE...42.4742J

(2014) suggested that treatment of betaine ameliorates NAFLD in the mice fed with a high-fat diet possibly by restoring the methylation capacity by increasing the SAM/SAH ratio and thereby reversing the abnormal expression of the genes involved in lipid metabolism, such as FAS (fatty acid synthase), ACOX (acyl-CoA oxidase), PPAR (peroxisome proliferator-activated receptor alpha) in the liver

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Lactobacillus fermentum ME-3 an antimicrobial and antioxidative probiotic